We report a one-step method for the synthesis of alkoxy substituted pyrazine derivatives. The process makes use of an improved acid-mediated coupling reaction to afford the products in good yields (70–90%). This method expands the scope to alkoxy substituted pyrazine structures that are poorly represented in literature.

中文翻译：

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方便的一步合成烷氧基取代的吡嗪衍生物

我们报告了一种合成烷氧基取代吡嗪衍生物的一步法。该过程利用改进的酸介导的偶联反应以良好的收率（70-90%）提供产品。这种方法将范围扩展到在文献中很少体现的烷氧基取代的吡嗪结构。