当前位置: X-MOL 学术J. Biomech. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
A limited number of slices yields comparable results to all slices in foot intrinsic muscle deterioration ratio on computed tomography and magnetic resonance imaging
Journal of Biomechanics ( IF 2.4 ) Pub Date : 2021-09-13 , DOI: 10.1016/j.jbiomech.2021.110750
Jennifer A Zellers 1 , Paul K Commean 2 , Ling Chen 3 , Michael J Mueller 1 , Mary K Hastings 1
Affiliation  

Diagnostic imaging modalities, like computed tomography (CT) and magnetic resonance imaging (MRI), can be used to assess in vivo muscle quality. Quantitative assessment using these techniques is time-intensive and costly due in part to extensive post-processing needs. The purpose of this study was to identify whether a subset of slices on CT and MRI would yield comparable results to the full number of slices for a measure of muscle quality (muscle deterioration ratio = fat volume/muscle volume) in the foot intrinsic muscles of people with diabetes and peripheral neuropathy. CT (0.6 mm slice thickness) and MRI (3.5 mm slice thickness) scans were obtained using previously described methods. The total number of slices acquired during the scan was compared to several conditions using a portion of slices. Bland-Altman plots and Lin’s concordance correlation coefficient were used to test agreement. Any condition using at least three slices yielded substantial to almost perfect agreement with the total number of slices on both CT and MRI (Range of Lin’s concordance correlation coefficient: 0.947–0.999). Using a single slice in the middle of the region of interest demonstrated poor to moderate agreement with the total number of slices. The findings of this study suggest that using a limited number of slices to quantify muscle deterioration ratio on CT or MRI is a viable way to balance the combined need for measurement accuracy with feasibility in research and clinical settings.



中文翻译:

在计算机断层扫描和磁共振成像上,有限数量的切片产生与足内在肌肉退化率的所有切片相当的结果

诊断成像方式,如计算机断层扫描 (CT) 和磁共振成像 (MRI),可用于评估体内肌肉质量。使用这些技术的定量评估是耗时且昂贵的,部分原因是广泛的后处理需求。本研究的目的是确定 CT 和 MRI 切片的子集是否会产生与用于测量足部内在肌肉肌肉质量(肌肉退化率 = 脂肪体积/肌肉体积)的全部切片数量相当的结果患有糖尿病和周围神经病变的人。使用先前描述的方法获得 CT(0.6 毫米切片厚度)和 MRI(3.5 毫米切片厚度)扫描。将扫描期间获得的切片总数与使用一部分切片的几种情况进行了比较。Bland-Altman 图和 Lin 的一致性相关系数用于检验一致性。使用至少三个切片的任何条件都与 CT 和 MRI 上的切片总数产生实质性甚至几乎完美的一致(Lin 一致性相关系数的范围:0.947–0.999)。在感兴趣区域的中间使用单个切片表明与切片总数的一致性差到中等。这项研究的结果表明,使用有限数量的切片来量化 CT 或 MRI 上的肌肉退化率是一种可行的方法,可以平衡测量精度的综合需求与研究和临床环境的可行性。使用至少三个切片的任何条件都与 CT 和 MRI 上的切片总数产生实质性甚至几乎完美的一致(Lin 一致性相关系数的范围:0.947–0.999)。在感兴趣区域的中间使用单个切片表明与切片总数的一致性差到中等。这项研究的结果表明,使用有限数量的切片来量化 CT 或 MRI 上的肌肉退化率是一种可行的方法,可以平衡测量精度的综合需求与研究和临床环境的可行性。使用至少三个切片的任何条件都与 CT 和 MRI 上的切片总数产生实质性甚至几乎完美的一致(Lin 一致性相关系数的范围:0.947–0.999)。在感兴趣区域的中间使用单个切片表明与切片总数的一致性差到中等。这项研究的结果表明,使用有限数量的切片来量化 CT 或 MRI 上的肌肉退化率是一种可行的方法,可以平衡测量精度的综合需求与研究和临床环境的可行性。

更新日期:2021-09-20
down
wechat
bug