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Common Variants of the OPG gene Are Associated with Osteoporosis Risk: A Meta-Analysis
Genetic Testing and Molecular Biomarkers ( IF 1.1 ) Pub Date : 2021-09-17 , DOI: 10.1089/gtmb.2020.0282 Xiaobin Li 1 , Junwen Cheng 1 , Bin Dong 1 , Xiaoping Yu 2 , Xiaona Zhao 1 , Zhikang Zhou 1
Genetic Testing and Molecular Biomarkers ( IF 1.1 ) Pub Date : 2021-09-17 , DOI: 10.1089/gtmb.2020.0282 Xiaobin Li 1 , Junwen Cheng 1 , Bin Dong 1 , Xiaoping Yu 2 , Xiaona Zhao 1 , Zhikang Zhou 1
Affiliation
Background: The RANKL/RANK/OPG signaling pathway plays a critical role in osteoclastogenesis and bone remodeling. The associations between sequence variants of the osteoprotegerin (OPG) gene and osteoporosis risk have been widely investigated but remain inconclusive.
中文翻译：
OPG 基因的常见变异与骨质疏松症风险相关：荟萃分析
背景： RANKL/RANK/OPG 信号通路在破骨细胞生成和骨重塑中起关键作用。骨保护素 ( OPG ) 基因的序列变体与骨质疏松症风险之间的关联已被广泛研究，但仍无定论。
更新日期：2021-09-23
中文翻译：
OPG 基因的常见变异与骨质疏松症风险相关：荟萃分析
背景： RANKL/RANK/OPG 信号通路在破骨细胞生成和骨重塑中起关键作用。骨保护素 ( OPG ) 基因的序列变体与骨质疏松症风险之间的关联已被广泛研究，但仍无定论。
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