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Potential Antiviral Properties of Industrially Important Marine Algal Polysaccharides and Their Significance in Fighting a Future Viral Pandemic
Viruses ( IF 3.8 ) Pub Date : 2021-09-13 , DOI: 10.3390/v13091817
Renu Geetha Bai 1 , Rando Tuvikene 1
Affiliation  

Over the decades, the world has witnessed diverse virus associated pandemics. The significant inhibitory effects of marine sulfated polysaccharides against SARS-CoV-2 shows its therapeutic potential in future biomedical applications and drug development. Algal polysaccharides exhibited significant role in antimicrobial, antitumor, antioxidative, antiviral, anticoagulant, antihepatotoxic and immunomodulating activities. Owing to their health benefits, the sulfated polysaccharides from marine algae are a great deal of interest globally. Algal polysaccharides such as agar, alginate, carrageenans, porphyran, fucoidan, laminaran and ulvans are investigated for their nutraceutical potential at different stages of infection processes, structural diversity, complexity and mechanism of action. In this review, we focus on the recent antiviral studies of the marine algae-based polysaccharides and their potential towards antiviral medicines.

中文翻译:

工业上重要的海藻多糖的潜在抗病毒特性及其在抗击未来病毒大流行中的意义

几十年来,世界见证了各种与病毒相关的流行病。海洋硫酸化多糖对 SARS-CoV-2 的显着抑制作用显示了其在未来生物医学应用和药物开发中的治疗潜力。藻多糖在抗微生物、抗肿瘤、抗氧化、抗病毒、抗凝血、抗肝毒性和免疫调节活性方面表现出重要作用。由于它们的健康益处,来自海藻的硫酸化多糖在全球范围内引起了极大的兴趣。研究了藻类多糖,如琼脂、藻酸盐、角叉菜胶、卟啉、岩藻多糖、海带多糖和海藻糖在感染过程的不同阶段、结构多样性、复杂性和作用机制的营养潜力。在这次审查中,
更新日期:2021-09-13
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