Background

Anterior communicating artery aneurysms are the second most common type of intracranial aneurysm and have a high incidence of rupture. Intraprocedural rupture can lead to a high mortality and morbidity rate, representing a major challenge in emergency endovascular treatment of ruptured anterior communicating artery aneurysms.

Methods

We performed a retrospective review of 344 consecutive patients with emergency endovascular treatment of ruptured anterior communicating artery aneurysms. Patients were grouped into intraprocedural rupture and non-intraprocedural rupture groups according to whether intraprocedural rupture occurred. Demographic and clinical factors, vessel-related factors and therapy-related factors were compared between the two groups.

Results

Intraprocedural rupture occurred in 11 patients (3.2%). Univariate analysis showed that hypertension, the occurrence of vasospasm, aneurysm size, aneurysm angle and a high aspect ratio value were significantly associated with intraprocedural rupture (P < 0.05). Multivariate analysis showed that hypertension odds ratio (OR, 9.799; P = 0.007), the occurrence of vasospasm (OR, 10.121; P = 0.002) and a high aspect ratio value (OR, 10.571; P = 0.006) were independent risk factors for intraprocedural rupture.

Conclusions

A history of hypertension, the occurrence of vasospasm and a high aspect ratio value are independent risk factors for intraprocedural rupture among patients with ruptured anterior communicating artery aneurysms.

中文翻译：

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前交通动脉瘤破裂急诊腔内治疗过程中发生破裂的危险因素

背景

前交通动脉瘤是第二常见的颅内动脉瘤类型，破裂发生率很高。术中破裂可导致高死亡率和发病率，是前交通动脉瘤破裂紧急血管内治疗的主要挑战。

方法

我们对 344 名连续接受前交通动脉瘤破裂紧急血管内治疗的患者进行了回顾性研究。根据是否发生术中破裂将患者分为术中破裂组和非术中破裂组。比较两组之间的人口统计学和临床​​因素、血管相关因素和治疗相关因素。

结果

11 名患者（3.2%）发生术中破裂。单因素分析显示，高血压、血管痉挛的发生、动脉瘤大小、动脉瘤角度和高纵横比值与术中破裂显着相关（P  < 0.05）。多变量分析显示，高血压比值比（OR，9.799；P  = 0.007）、血管痉挛的发生（OR，10.121；P  = 0.002）和高纵横比值（OR，10.571；P  = 0.006）是独立危险因素。术中破裂。

结论

高血压病史、发生血管痉挛和高纵横比值是前交通动脉瘤破裂患者术中破裂的独立危险因素。