In this paper, a capillary coated with poly(glycidyl methacrylate) nanoparticles (PGMA NPs) was prepared and applied to construct a capillary electrophoresis (CE) enantioseparation system with glucosyl-β-cyclodextrin (Glu-β-CD) as a chiral selector. The PGMA NP coating can be easily introduced through a simple ring-opening reaction. Two basic drugs were used as models to evaluate the separation performance of the PGMA coating. Under the optimal conditions selected, the separation of the two enantiomers was obtained.

中文翻译：

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在毛细管电泳中使用 Glu-β-CD 作为手性选择剂对聚甲基丙烯酸缩水甘油酯纳米涂层进行手性分离的评价

在本文中，制备了涂有聚甲基丙烯酸缩水甘油酯纳米颗粒 (PGMA NPs) 的毛细管，并将其用于构建以葡萄糖基-β-环糊精 (Glu - β -CD) 作为手性选择剂的毛细管电泳 (CE) 对映分离系统。PGMA NP 涂层可以通过简单的开环反应轻松引入。以两种碱性药物为模型来评估 PGMA 涂层的分离性能。在选定的最佳条件下，实现了两种对映异构体的分离。