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Green synthesis of titanium dioxide nanoparticles using Laurus nobilis (bay leaf): antioxidant and antimicrobial activities
Applied Nanoscience ( IF 3.869 ) Pub Date : 2021-09-12 , DOI: 10.1007/s13204-021-02065-2
V. Devi Rajeswari 1 , Emad M. Eed 2 , Ashraf Elfasakhany 3 , Irfan Anjum Badruddin 4 , Sarfaraz Kamangar 4 , Kathirvel Brindhadevi 5, 6
Affiliation  

Amalgamation of nanoparticles using “Green Technology” is an intensive field of research due to the increase in the need for the development of new antimicrobial materials. This method is meritorious both in environmental and economic aspects. In the present study, synthesis of titanium dioxide nanoparticles (TiO2 NPs) was done using the aqueous extract of Laurus nobilis (bay leaf). The characterization was done using UV–visible absorption spectroscopy, X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), particle size, and zeta potential analyses. Successful production of nanoparticles was confirmed by the presence of spherical-shaped TiO2 NPs with the size of ~ 100 nm. The nanoparticles were tested against pathogens to determine their antibacterial and antifungal activities. The antimicrobial and antifungal activities with various concentrations for the generated TiO2 NPs were investigated and the results showed that the synthesised nanoparticles manifested a good inhibitory activity against both the tested bacteria and the fungal strain. Bacillus subtilis and Aspergillus niger showed better zone of inhibition against nanoparticle. The observation is that the inhibition zone increases proportionately with the increased nanoparticles concentration. The as-prepared nanoparticles were also subjected to free radical scavenging ability using DPPH and hydrogen peroxide assays. TiO2 NPs revealed a strong antioxidant activity when compared with ascorbic acid standard. Current study concludes that the concocted TiO2 NPs, using L. nobilis bay leaf, can be scaled up for large-scale industrial production, which would be eco-friendly, economic with a high productivity.



中文翻译:

使用月桂叶(月桂叶)绿色合成二氧化钛纳米颗粒:抗氧化和抗菌活性

由于对开发新抗菌材料的需求增加,使用“绿色技术”的纳米粒子的合并是一个密集的研究领域。这种方法在环境和经济方面都有优点。在本研究中,二氧化钛纳米颗粒的合成(的TiO 2纳米粒子),使用的水提取液进行月桂(月桂叶)。使用紫外可见吸收光谱、X 射线衍射 (XRD)、傅里叶变换红外光谱 (FTIR)、扫描电子显微镜 (SEM)、粒度和 zeta 电位分析进行表征。球形TiO 2的存在证实了纳米颗粒的成功生产NPs 的大小约为 100 nm。对纳米颗粒进行了针对病原体的测试,以确定它们的抗菌和抗真菌活性。研究了不同浓度下生成的 TiO 2 NPs的抗菌和抗真菌活性,结果表明合成的纳米颗粒对受试细菌和真菌菌株均表现出良好的抑制活性。枯草芽孢杆菌黑曲霉对纳米颗粒显示出更好的抑制区域。观察结果是抑菌圈随着纳米颗粒浓度的增加成比例地增加。使用 DPPH 和过氧化氢测定法也使所制备的纳米颗粒具有清除自由基的能力。二氧化钛2与抗坏血酸标准品相比,NPs 显示出很强的抗氧化活性。目前的研究得出结论,使用L. nobilis月桂叶调制的 TiO 2 NPs可以扩大规模用于大规模工业生产,这将是环保、经济和高生产力的。

更新日期:2021-09-13
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