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Azobenzene-isoxazoline as photopharmacological ligand for optical control of insect GABA receptor and behavior
Pest Management Science ( IF 3.8 ) Pub Date : 2021-09-13 , DOI: 10.1002/ps.6641
Zhi Qiao 1 , Yunfan Ji 1 , Yongchao Zhang 1 , Zhong Li 1 , Zhiping Xu 1 , Xusheng Shao 1, 2
Affiliation  

Photopharmacology is a fast-growing photonics-based technology, which realizes the high-resolution regulation of drugs in time and space through light. The purpose of this research was to introduce photochromic groups into the isoxazoline structure to realize the regulation of γ-Aminobutyric acid receptors (GABARs) targeting insect behavior.

中文翻译:

偶氮苯异恶唑啉作为光药理配体对昆虫 GABA 受体和行为的光学控制

光药理学是一种快速发展的基于光子学的技术,它通过光实现对药物在时间和空间上的高分辨率调控。本研究的目的是在异恶唑啉结构中引入光致变色基团,实现针对昆虫行为的γ-氨基丁酸受体(GABARs)的调控。
更新日期:2021-09-13
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