Aqueous solutions of human hemoglobin have been studied by the multi-angle static light scattering method. The tendency of sickle-shaped erythrocytes to aggregate has been attributed, in particular, to their particular shape. Debye, asymmetry, and Zimm methods were used to process the experimental data. The weights of the scattering particles and molecular dimensions were estimated. The structure of the hemoglobin molecule is presumed to become elongated. The results obtained by the Zimm method are in best agreement with previous data. The large size of the scattering particles obtained by the asymmetry and Debye methods may be related to dissociation of hemoglobin, leading to a reversible dynamic process, whose equilibrium is a function of the protein concentration.

已经通过多角度静态光散射方法研究了人血红蛋白的水溶液。镰状红细胞聚集的趋势尤其归因于它们的特定形状。使用德拜、不对称和 Zimm 方法处理实验数据。估计散射粒子的重量和分子尺寸。推测血红蛋白分子的结构被拉长。Zimm 方法获得的结果与以前的数据最吻合。不对称法和德拜法获得的散射粒子的大尺寸可能与血红蛋白的解离有关，导致可逆的动态过程，其平衡是蛋白质浓度的函数。