Abstract

The coupling reactions of amines into imines oxidized by persulfate with the assistance of ultrasound were carried out. The reaction conditions were optimized and the effect of ultrasonic was also investigated. The results indicated that Na₂S₂O₈ in combination with ultrasound possessed excellent oxidative performance, which made this transformation smoothly proceed under the conditions of solvent-/catalyst- free, and low reaction temperature, giving excellent yields of imines in short reaction time. Our procedure had high reaction tolerance to various primary benzylic amines, demonstrating good universality. Furthermore, a tentative reaction mechanism and pathway were proposed.

摘要

在超声的辅助下，进行了胺与过硫酸盐氧化的亚胺的偶联反应。对反应条件进行了优化，并研究了超声波的影响。结果表明，Na ₂ S ₂ O ₈与超声相结合具有优异的氧化性能，使该转变在无溶剂/无催化剂、低反应温度条件下顺利进行，反应时间短，亚胺收率高。 . 我们的程序对各种伯苄胺具有很高的反应耐受性，表现出良好的普遍性。此外，还提出了初步的反应机理和途径。