Due to drug addiction and the emergence of antibiotic resistance in pathogens, the disease load and medication intake have risen worldwide. The alternative treatment for drug-resistant infections is Nano formulation-based antimicrobial agents. The plant extract of Conocarpus Lancifolius fruits was used to synthesize silver nanoparticles in the current study, and it was further employed as an antimicrobial and anticancer agent. Nanoparticles have been characterized by UV–visible spectrometer revealed the notable peak of λ_max = 410–442 nm, which confirms the reduction of silver ion to elemental silver nanoparticles, and the biological moieties in the synthesis were further confirmed by FTIR analysis. The stability and crystalline nature of materials were approved by XRD analysis and expected the size of the nanomaterials of 21 to 173 nm analyzed by a nanophox particle-size analyzer. In vitro, synthesized materials act as an antibacterial agent against Streptococcus pneumonia and Staphylococcus aureus. The inhibition zones of 18 and 24 mm have been estimated to be antibacterial activity against both bacteria. The potency of up to 100% of AgNPs for bacterial strains was incubated overnight at 60 μg/ml. Based on our results, biogenic AgNPs reveal significant activity against fungal pathogen Rhizopusus stolonifera and Aspergillus flavus that cause leading infectious diseases. Additionally, nanomaterials were biocompatible and demonstrated the potential anticancer activities against MDA MB-231 cells after 24-hour exposure.

由于药物成瘾和病原体抗生素耐药性的出现，全世界的疾病负荷和药物摄入量都在上升。耐药感染的替代治疗方法是基于纳米制剂的抗菌剂。本研究利用Conocarpus Lancifolius果实的植物提取物合成银纳米颗粒，并进一步将其用作抗菌和抗癌剂。通过紫外-可见光谱仪对纳米颗粒进行表征，显示出 λ _max = 410-442 nm 的显着峰，这证实了银离子还原为单质银纳米颗粒，并且通过 FTIR 分析进一步证实了合成中的生物部分。材料的稳定性和结晶性质通过 XRD 分析得到证实，并通过 nanophox 粒度分析仪分析预计纳米材料的尺寸为 21 至 173 nm。在体外，合成材料可作为针对肺炎链球菌和金黄色葡萄球菌的抗菌剂。据估计，18 毫米和 24 毫米的抑菌圈对这两种细菌均具有抗菌活性。 AgNP 在 60 μg/ml 浓度下培养过夜，对细菌菌株的效力高达 100%。根据我们的结果，生物 AgNPs 显示出对引起主要传染病的真菌病原体匍匐根霉和黄曲霉具有显着的活性。此外，纳米材料具有生物相容性，并且在暴露 24 小时后显示出对 MDA MB-231 细胞的潜在抗癌活性。