Background:Increasing physical activity (PA) in those who have memory concerns requires innovative approaches. Objective:To compare in this randomized controlled trial (RCT) the effects on PA, adherence, and fitness of two approaches to deliver a 6-month home-based PA program in older, inactive individuals at risk of cognitive decline. Methods:Individuals (n = 52) aged 60–85 years, inactive with mild cognitive impairment or subjective cognitive decline were recruited from the community and memory clinics. Randomization was to 6 months of 150 min/week moderate intensity PA with either: goal-setting with mentor support; or education and peer contact. A subset of participants (n = 36) continued for a further 6 months. PA, moderate and vigorous PA, and secondary outcomes, fitness, goal performance/satisfaction and self-efficacy were assessed at baseline, 6 and 12 months. Modelling of primary and secondary outcomes was conducted with linear mixed models. Results:Participants were mean age (±sd) 70.1 (6.4) years. Six-month retention was 88.5%(n = 46). No significant between-group differences were observed for PA or fitness. Post-hoc combined group data showed a significant, moderate-large effect size increase in PA with time. PA increased by a mean 1,662 (943, 2383) steps/day (95%CI) and 1,320 (603, 2037) steps/day at 6 and 12 months (p < 0.001). Median (quartiles Q1-Q3) 6 and 6–12 month combined group adherence was 88.9 (74.4–95.7)%and 84.6 (73.9–95.4)%respectively. Conclusion:In this target group, no differences were detected between groups both intervention strategies were highly effective in increasing PA and fitness.

中文翻译：

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一项关于为期 6 个月的居家体育活动计划的随机对照试验，该计划有个人目标设定和志愿者导师对有认知衰退风险的不活动老年人的体育活动、依从性和身体健康的影响：INDIGO 研究

背景：增加有记忆问题的人的身体活动 (PA) 需要创新的方法。目的：在这项随机对照试验 (RCT) 中，比较在有认知能力下降风险的年长、不活动的个体中实施 6 个月家庭 PA 计划的两种方法对 PA、依从性和健康的影响。方法：从社区和记忆诊所招募年龄在 60-85 岁、不活动且有轻度认知障碍或主观认知下降的个体（n = 52）。随机化为 6 个月 150 分钟/周的中等强度 PA，其中之一是：在导师支持下设定目标；或教育和同伴联系。一部分参与者 (n = 36) 又持续了 6 个月。PA、中度和剧烈的 PA，以及次要结果、健康、在基线、6 个月和 12 个月时评估目标表现/满意度和自我效能感。主要和次要结果的建模使用线性混合模型进行。结果：参与者的平均年龄 (±sd) 为 70.1 (6.4) 岁。六个月的保留率为 88.5%（n = 46）。没有观察到 PA 或健身的显着组间差异。事后联合组数据显示，随着时间的推移，PA 的影响大小显着增加。在 6 个月和 12 个月时，PA 平均增加 1,662 (943, 2383) 步/天 (95% CI) 和 1,320 (603, 2037) 步/天（p < 0.001）。中位（四分位数 Q1-Q3）6 个月和 6-12 个月的组合依从性分别为 88.9 (74.4-95.7)% 和 84.6 (73.9-95.4)%。结论：在该目标组中，两组之间没有检测到差异，两种干预策略在增加 PA 和健康方面都非常有效。