Multiple objective assessments have been used to assess the activity of keloids to compare different therapeutic regimens and facilitate the best individual treatment choice for patients, but none of them are standardized. A multimodal photoacoustic/ultrasonic (PA/US) imaging system, including photoacoustic imaging, elastography, ultra-micro-angiography, and conventional US technologies (gray scale US, color Doppler US, and power Doppler US), was applied to evaluate keloids by a radiologist. Growing stages were defined by patients, and Vancouver Scar Scale (VSS) was assessed by a plastic surgeon. A comprehensive model based on multimodal ultrasound parameters (poor-echo pattern, high vascular density, decreased elasticity, and low SO within the keloid) and VSS might be a potential indicator of active keloids, comparing with VSS alone. The multimodal PA/US imaging system could be a promising technique for keloids assessment.

中文翻译：

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多模态光声/超声成像系统评价瘢痕疙瘩的活性

多种客观评估已被用来评估疤痕疙瘩的活性，以比较不同的治疗方案并促进患者最佳的个体化治疗选择，但没有一个是标准化的。多模态光声/超声（PA/US）成像系统，包括光声成像、弹性成像、超微血管造影和传统超声技术（灰度超声、彩色多普勒超声和能量多普勒超声），用于评估疤痕疙瘩：放射科医生。生长阶段由患者定义，温哥华疤痕量表（VSS）由整形外科医生评估。与单独的 VSS 相比，基于多模态超声参数（回声模式差、血管密度高、弹性降低、瘢痕疙瘩内 SO 低）和 VSS 的综合模型可能是活动性瘢痕疙瘩的潜在指标。多模态 PA/US 成像系统可能是一种有前景的疤痕疙瘩评估技术。