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In Silico Evaluation of Bilinear Elastoplastic Coronary Artery Stents
Advanced Engineering Materials ( IF 3.4 ) Pub Date : 2021-09-12 , DOI: 10.1002/adem.202100800 Zakieh Alihemmati 1 , Bahman Vahidi 1 , Amirala Bakhshian Nik 2 , Roza Vaez Ghaemi 3 , Yasin Taghizadeh 1
Advanced Engineering Materials ( IF 3.4 ) Pub Date : 2021-09-12 , DOI: 10.1002/adem.202100800 Zakieh Alihemmati 1 , Bahman Vahidi 1 , Amirala Bakhshian Nik 2 , Roza Vaez Ghaemi 3 , Yasin Taghizadeh 1
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Mechanical responses of the endovascular stent determine the arterial homeostasis and vulnerability of the atherosclerotic plaque. Given the various plaque components when the stent is deployed, the stent may apply excessive stress to the lesion and cause plaque rupture. Herein, using the interaction between the Palmaz–Schatz stent with two stent biomaterials, stainless steel, and magnesium alloy, and three different types of plaque, namely hypocellular, hypercellular, and calcified, are studied. An implicit finite element method is used to simulate and analyze the stress and strain acting on the stents, artery, and plaques. The Mooney–Rivlin hyperelastic material model is considered to study the responses of each component. The results reveal that stainless-steel stents applied a higher level of stress to the plaques and vessel wall, which may lead to vascular damage and plaque rupture. However, a magnesium alloy stent with the similar design and geometrical parameters generates less stress on the plaque and artery. Interestingly, a minor improvement in magnesium alloy stents, increasing the strut thickness, can enhance the stent performance and lower the applied stresses to the vasculature and plaque, making them an ideal choice of material for stenting applications.
中文翻译：
双线性弹性冠状动脉支架的计算机评估
血管内支架的机械反应决定了动脉内稳态和动脉粥样硬化斑块的易损性。当支架展开时考虑到各种斑块成分，支架可能对病变施加过大的应力并导致斑块破裂。在此，利用 Palmaz-Schatz 支架与两种支架生物材料、不锈钢和镁合金以及三种不同类型的斑块（即细胞少、细胞过多和钙化）之间的相互作用进行了研究。隐式有限元法用于模拟和分析作用在支架、动脉和斑块上的应力和应变。考虑使用 Mooney-Rivlin 超弹性材料模型来研究每个组件的响应。结果表明，不锈钢支架对斑块和血管壁施加了更高水平的应力，这可能导致血管损伤和斑块破裂。然而，具有相似设计和几何参数的镁合金支架对斑块和动脉产生的应力较小。有趣的是，镁合金支架的微小改进（增加支柱厚度）可以提高支架性能并降低对脉管系统和斑块施加的应力，使其成为支架应用的理想材料选择。
更新日期：2021-09-12
中文翻译：
双线性弹性冠状动脉支架的计算机评估
血管内支架的机械反应决定了动脉内稳态和动脉粥样硬化斑块的易损性。当支架展开时考虑到各种斑块成分，支架可能对病变施加过大的应力并导致斑块破裂。在此，利用 Palmaz-Schatz 支架与两种支架生物材料、不锈钢和镁合金以及三种不同类型的斑块（即细胞少、细胞过多和钙化）之间的相互作用进行了研究。隐式有限元法用于模拟和分析作用在支架、动脉和斑块上的应力和应变。考虑使用 Mooney-Rivlin 超弹性材料模型来研究每个组件的响应。结果表明，不锈钢支架对斑块和血管壁施加了更高水平的应力，这可能导致血管损伤和斑块破裂。然而，具有相似设计和几何参数的镁合金支架对斑块和动脉产生的应力较小。有趣的是，镁合金支架的微小改进（增加支柱厚度）可以提高支架性能并降低对脉管系统和斑块施加的应力，使其成为支架应用的理想材料选择。
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