Bioethanol is an alternative to motor fuel, generated through the fermentation of sugars released from the hydrolyzed cellulosic material. For efficient ethanol production, total utilization of sugars needs an improved fermentation approach i.e. Simultaneous Saccharification and Co-fermentation (SSCF). SSCF is the current, advanced, close to commercialization approach that is being continuously improved for high ethanol titer, total sugar (hexose + pentose) utilization, high mass transfer, reducing the feedback inhibition, and one-pot conversion strategies. The major improvement strategies such as enhancing the saccharification rate, engineering microbes for co-fermentation, enhancing mass transfer through impeller designing, and the role of conditional factors on the SSCF process are reviewed in this study.

生物乙醇是发动机燃料的替代品，通过发酵水解纤维素材料释放的糖类产生。为了有效地生产乙醇，糖的总利用需要改进的发酵方法，即同步糖化和共发酵 (SSCF)。SSCF 是当前的、先进的、接近商业化的方法，它正在不断改进以实现高乙醇滴度、总糖（己糖 + 戊糖）利用、高传质、减少反馈抑制和一锅法转化策略。本研究综述了主要的改进策略，例如提高糖化率、共发酵工程微生物、通过叶轮设计增强传质以及条件因素对 SSCF 过程的作用。