Autism spectrum disorder (ASD) is characterized by hallmark impairments in social functioning. Nevertheless, nonsocial cognition, including hippocampus-dependent spatial reasoning and episodic memory, is also commonly impaired in ASD. ASD symptoms typically emerge between 12 and 24 months of age, a time window associated with critical developmental events in the hippocampus. Despite this temporal overlap and evidence of hippocampal structural abnormalities in ASD individuals, relatively few human studies have focused on hippocampal function in ASD. Herein, we review the existing evidence for the involvement of the hippocampus in ASD and highlight the hippocampus as a promising area of interest for future research in ASD.

自闭症谱系障碍 (ASD) 的特征是社会功能的标志性障碍。然而，非社会认知，包括海马依赖的空间推理和情景记忆，在 ASD 中也普遍受损。ASD 症状通常出现在 12 到 24 个月之间，这是一个与海马关键发育事件相关的时间窗口。尽管在 ASD 个体中存在这种时间重叠和海马结构异常的证据，但相对较少的人类研究关注 ASD 中的海马功能。在此，我们回顾了海马体参与 ASD 的现有证据，并强调海马体是未来 ASD 研究的一个有希望的领域。