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Supercritical fluid extraction of cannabinoids (THC and CBD) from four different strains of cannabis grown in different regions
The Journal of Supercritical Fluids ( IF 3.4 ) Pub Date : 2021-09-12 , DOI: 10.1016/j.supflu.2021.105410
Umut Karğılı 1, 2 , Ezgi Aytaç 3
Affiliation  

The aim of this study is to investigate the cannabinoid content of different types of cannabis plants grown in different climatic regions under different supercritical extraction conditions. Extractions were carried out at different pressures of 15 and 33 MPa and 40 and 60 °C temperatures. All conditions were tested both in the presence and absence of co-solvent ethanol. Extraction yield was highly dependent on pressure, co-solvent, climatic conditions and strain. The cannabinoid composition of the extracts was determined with HPLC analyses. The highest CBD and THC yields were obtained from Papatya strain (90.82% THC, 3.71% CBD) and Elnur strain (58.22% THC, 3.29% CBD). Narlı strain yielded the highest CBD (7.70%) result. This work demonstrates the effectiveness of the climatic conditions on the strains with supercritical extraction of cannabinoids. It is the first study to show the different climatic conditions effect on the yield of CBD and THC in different strains.



中文翻译:

从不同地区种植的四种不同大麻菌株中提取大麻素(THC 和 CBD)的超临界流体

本研究的目的是调查在不同超临界提取条件下生长在不同气候区域的不同类型大麻植物的大麻素含量。在 15 和 33 MPa 的不同压力以及 40 和 60 °C 的温度下进行萃取。在存在和不存在共溶剂乙醇的情况下测试所有条件。提取率高度依赖于压力、共溶剂、气候条件和应变。提取物的大麻素成分通过 HPLC 分析确定。最高的 CBD 和 THC 产量来自 Papatya 菌株(90.82% THC,3.71% CBD)和 Elnur 菌株(58.22% THC,3.29% CBD)。Narlı 菌株产生了最高的 CBD (7.70%) 结果。这项工作证明了气候条件对大麻素超临界提取菌株的有效性。这是第一项显示不同气候条件对不同菌株 CBD 和 THC 产量影响的研究。

更新日期:2021-09-16
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