Approximately 67% of U.S. households have pets. Limited data are available on SARS-CoV-2 in pets. We assessed SARS-CoV-2 infection in pets during a COVID-19 household transmission investigation. Pets from households with ≥1 person with laboratory-confirmed COVID-19 were eligible for inclusion from April–May 2020. We enrolled 37 dogs and 19 cats from 34 households. All oropharyngeal, nasal, and rectal swabs tested negative by rRT-PCR; one dog’s fur swabs (2%) tested positive by rRT-PCR at the first sampling. Among 47 pets with serological results, eight (17%) pets (four dogs, four cats) from 6/30 (20%) households had detectable SARS-CoV-2 neutralizing antibodies. In households with a seropositive pet, the proportion of people with laboratory-confirmed COVID-19 was greater (median 79%; range: 40–100%) compared to households with no seropositive pet (median 37%; range: 13–100%) (p = 0.01). Thirty-three pets with serologic results had frequent daily contact (≥1 h) with the index patient before the person’s COVID-19 diagnosis. Of these 33 pets, 14 (42%) had decreased contact with the index patient after diagnosis and none were seropositive; of the 19 (58%) pets with continued contact, four (21%) were seropositive. Seropositive pets likely acquired infection after contact with people with COVID-19. People with COVID-19 should restrict contact with pets and other animals.

中文翻译：

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对人类 COVID-19 确诊病例家庭中宠物的 SARS-CoV-2 感染和血清阳性进行的一项健康调查——犹他州和威斯康星州，2020 年

大约 67% 的美国家庭养宠物。关于宠物 SARS-CoV-2 的可用数据有限。我们在 COVID-19 家庭传播调查期间评估了宠物中的 SARS-CoV-2 感染情况。2020 年 4 月至 5 月期间，有 ≥ 1 人经实验室确诊的 COVID-19 患者的家庭的宠物符合纳入资格。我们招募了来自 34 个家庭的 37 只狗和 19 只猫。所有口咽、鼻腔和直肠拭子的 rRT-PCR 检测结果均为阴性；第一次采样时，一只狗的皮毛拭子 (2%) 通过 rRT-PCR 检测呈阳性。在有血清学结果的 47 只宠物中，来自 6/30 (20%) 家庭的 8 只 (17%) 宠物（四只狗，四只猫）检测到 SARS-CoV-2 中和抗体。与没有血清阳性宠物的家庭相比，在有血清阳性宠物的家庭中，实验室确诊的 COVID-19 患者比例更高（中位数 79%；范围：40-100%）（中位数 37%；范围：13-100%） ）（p = 0.01）。33 只具有血清学结果的宠物在被确诊为 COVID-19 之前与指示患者每天频繁接触（≥1 小时）。在这 33 只宠物中，有 14 只（42%）在诊断后减少了与指标患者的接触，并且没有一只宠物呈血清阳性；在持续接触的 19 只宠物（58%）中，有 4 只（21%）呈血清反应阳性。血清呈阳性的宠物可能在与 COVID-19 感染者接触后受到感染。COVID-19 感染者应限制与宠物和其他动物的接触。