Background. Wearable sensors allow for direct measurement of upper limb (UL) performance in daily life. Objective. To map the trajectory of UL performance and its relationships to other factors post-stroke. Methods. Participants (n = 67) with first stroke and UL paresis were assessed at 2, 4, 6, 8, 12, 16, 20, and 24 weeks after stroke. Assessments captured UL impairment (Fugl-Meyer), capacity for activity (Action Research Arm Test), and performance of activity in daily life (accelerometer variables of use ratio and hours of paretic limb activity), along with other potential modifying factors. We modeled individual trajectories of change for each measurement level and the moderating effects on UL performance trajectories. Results. Individual trajectories were best fit with a 3-parameter logistic model, capturing the rapid growth early after stroke within the longer data collection period. Plateaus (90% of asymptote) in impairment (bootstrap mean ± SE: 32 ± 4 days post-stroke) preceded those in capacity (41 ± 4 days). Plateau in performance, as measured by the use ratio (24 ± 5 days), tended to precede plateaus in impairment and capacity. Plateau in performance, as measured by hours of paretic activity (41 ± 6 days), occurred at a similar time to that of capacity and slightly lagged impairment. Modifiers of performance trajectories were capacity, concordance, UL rehabilitation, depressive symptomatology, and cognition. Conclusions. Upper limb performance in daily life approached plateau 3 to 6 weeks post-stroke. Individuals with stroke started to achieve a stable pattern of UL use in daily life early, often before neurological impairments and functional capacity started to stabilize.

背景。可穿戴传感器允许直接测量日常生活中的上肢 (UL) 性能。客观的。映射 UL 性能的轨迹及其与中风后其他因素的关系。方法。在中风后 2、4、6、8、12、16、20 和 24 周评估首次中风和 UL 麻痹的参与者 (n = 67)。评估捕获了 UL 损伤 (Fugl-Meyer)、活动能力 (Action Research Arm Test) 和日常生活中的活动表现（使用比率的加速度计变量和瘫痪肢体活动小时数），以及其他潜在的修改因素。我们对每个测量级别的变化轨迹以及对 UL 性能轨迹的调节作用进行了建模。结果。个人轨迹最适合 3 参数逻辑模型，在较长的数据收集期内捕获中风后早期的快速增长。损伤的高原（90% 的渐近线）（引导平均值 ± SE：中风后 32 ± 4 天）先于能力障碍（41 ± 4 天）。以使用率（24 ± 5 天）衡量的性能平稳期往往先于损伤和容量的平稳期。以麻痹活动小时数（41 ± 6 天）衡量的表现平台期发生在与能力相似的时间和轻微滞后的损伤。绩效轨迹的修正因素是能力、一致性、UL 康复、抑郁症状和认知。结论。日常生活中的上肢表现在中风后 3 至 6 周接近平台期。中风患者在日常生活中很早就开始实现稳定的 UL 使用模式，通常是在神经损伤和功能能力开始稳定之前。