The herpes simplex virus 1 protein ICP4 acts as both an activator and repressor of host genome transcription during infection,Molecular and Cellular Biology

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The herpes simplex virus 1 protein ICP4 acts as both an activator and repressor of host genome transcription during infection
Molecular and Cellular Biology ( IF 3.2 ) Pub Date : 2021-07-12 , DOI: 10.1128/mcb.00171-21
Thomas Rivas ₁ , James A Goodrich ₁ , Jennifer F Kugel ₁

Affiliation

Infection by herpes simplex virus 1 (HSV-1) impacts nearly all steps of host cell gene expression. The regulatory mechanisms by which this occurs, and the interplay between host and viral factors, have yet to be fully elucidated. We investigated how the ...

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