Beyond Self-Resistance: ABCF ATPase LmrC Is a Signal-Transducing Component of an Antibiotic-Driven Signaling Cascade Accelerating the Onset of Lincomycin Biosynthesis,mBio

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Beyond Self-Resistance: ABCF ATPase LmrC Is a Signal-Transducing Component of an Antibiotic-Driven Signaling Cascade Accelerating the Onset of Lincomycin Biosynthesis
mBio ( IF 5.1 ) Pub Date : 2021-09-07 , DOI: 10.1128/mbio.01731-21
Marketa Koberska ₁ , Ludmila Vesela _{1,

2} , Vladimir Vimberg ₁ , Jakub Lenart ₁ , Jana Vesela ₁ , Zdenek Kamenik ₃ , Jiri Janata ₃ , Gabriela Balikova Novotna ₁

Affiliation

Resistance proteins are perceived as mechanisms protecting bacteria from the inhibitory effect of their produced antibiotics or antibiotics from competitors. Here, we report that antibiotic resistance proteins regulate lincomycin biosynthesis in response ...

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