Best Practice & Research Clinical Endocrinology & Metabolism ( IF 6.1 ) Pub Date : 2021-09-10 , DOI: 10.1016/j.beem.2021.101576 Angela H E M Maas 1
Menopause transition marks an important phase in life when cardiovascular risk in women gradually takes an adverse turn. Although menopausal hormone therapy has gained a negative appreciation over the last decades, its value in the treatment of disabling vasomotor symptoms is still undisputed. Cardiovascular risk assessment has become a matter of precision medicine, which is helpful for safe menopausal hormone therapy prescription. With a multidisciplinary approach the current available hormone regimens can be even given to women at intermediate cardiovascular risk, when risk factors such as hypertension and dyslipidemia are adequately monitored and treated.
中文翻译:
激素治疗和心血管疾病:利弊
更年期过渡标志着生命中的一个重要阶段,女性的心血管风险逐渐发生逆转。尽管绝经期激素疗法在过去几十年中获得了负面评价,但其在治疗致残血管舒缩症状方面的价值仍然是无可争议的。心血管风险评估已成为精准医学问题,有助于制定安全的更年期激素治疗处方。通过多学科方法,当高血压和血脂异常等风险因素得到充分监测和治疗时,目前可用的激素治疗方案甚至可以用于处于中等心血管风险的女性。