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Bevacizumab and gastrointestinal perforations: a review from the FDA Adverse Event Reporting System (FAERS) database
Alimentary Pharmacology & Therapeutics ( IF 6.6 ) Pub Date : 2021-09-09 , DOI: 10.1111/apt.16601
Thomas A Wichelmann 1 , Sufyan Abdulmujeeb 1 , Eli D Ehrenpreis 1
Affiliation  

Bevacizumab is used in the treatment of advanced malignancies and has a “black box” warning for gastrointestinal perforations. Despite this known side effect, there are no large descriptive series of patients who experience bevacizumab-induced gastrointestinal perforations.

中文翻译:

贝伐单抗和胃肠道穿孔:来自 FDA 不良事件报告系统 (FAERS) 数据库的综述

贝伐珠单抗用于治疗晚期恶性肿瘤,对胃肠道穿孔有“黑框”警告。尽管有这种已知的副作用,但没有大量描述性系列患者经历贝伐单抗引起的胃肠道穿孔。
更新日期:2021-10-27
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