Silver or palladium shelled gold nanoparticles were fused into alloy nanoparticles by pulsed-laser irradiation. The alloy nanoparticles could carry antibodies on their surfaces without affecting their immune functionalities and interact selectively with antigens on a blotting membrane. Silver or palladium ions desorbed from the alloy nanoparticles as reporter ions upon the UV laser irradiation in a mass spectrometer.

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中文翻译：

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金银和金钯合金纳米颗粒作为免疫传感的质量探针

银或钯壳金纳米粒子通过脉冲激光照射融合成合金纳米粒子。合金纳米粒子可以在其表面携带抗体而不影响其免疫功能，并选择性地与印迹膜上的抗原相互作用。在质谱仪中的紫外激光照射下，银或钯离子作为报告离子从合金纳米颗粒中解吸出来。

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