Screen-printed carbon electrodes (SPCEs) were fabricated and compared with the commercial DS 110 (DropSens). In addition to the classic cyclic voltammetry (CV) of K₃[Fe(CN)₆], a method using widely available Bausch + Lomb and Tylenol was developed for comprehensive evaluation of the electrochemical performance of SPCEs. Scanning electron microscope (SEM) images showed that the graphite surface of the in-house SPCEs, which acted as reaction surface, was covered by grainy binders thus less reactive than DS 110. X-ray photoelectron (XPS) spectra indicated that both were composed primarily of graphite (> 85%), but the concentrations of S (detected in DS110 only), N and Cl in the less-electroactive binders differed. The CV using K₃[Fe(CN)₆] as probe revealed that the peak-to-peak separation of the in-house SPCE (0.140 V) was further apart than that of DS 110 (0.075 V). The oxidation and reduction peak currents of the in-house SPCE were 73% and 82% of that of the DS 110, respectively. When CV was applied to the determination of acetaminophen in Tylenol (product label concentration: 661 mmol/L) using Bausch + Lomb solution with 1 mol/L KCl as the buffer, DS 110 showed better sensitivity, but the in-house SPCE was stable and more precise. Though DS 110 displayed higher current and thus more sensitive, the in-house SPCE current was stable and thus more precise. The concentrations obtained from oxidation and reduction peaks were (775 ± 80) mmol/L and (686 ± 322) mmol/L for DS 110, and (637 ± 39) mmol/L and (713 ± 139) mmol/L for in-house SPCE, respectively. Moreover, DS 110 exhibited two large unknown peaks and thus less reliable in the acetaminophen-in-Tylenol CV test. Determination of acetaminophen in real Tylenol sample was helpful as additional quality control in SPCEs fabrication.

制造丝网印刷碳电极 (SPCE) 并与商业 DS 110 (DropSens) 进行比较。除了经典的 K ₃ [Fe(CN) ₆ ]循环伏安法 (CV) 外，还开发了一种使用广泛可用的博士伦和泰诺的方法，用于综合评估 SPCE 的电化学性能。扫描电子显微镜 (SEM) 图像显示，作为反应表面的内部 SPCE 的石墨表面被颗粒状粘合剂覆盖，因此反应性低于 DS 110。 X 射线光电子 (XPS) 光谱表明两者都是组成的主要是石墨 (> 85%)，但电活性较低的粘合剂中 S（仅在 DS110 中检测到）、N 和 Cl 的浓度不同。使用 K ₃ [Fe(CN) ₆的 CV] 作为探针显示，内部 SPCE (0.140 V) 的峰间分离比 DS 110 (0.075 V) 的峰间分离更远。内部 SPCE 的氧化和还原峰值电流分别是 DS 110 的 73% 和 82%。当使用以 1 mol/L KCl 为缓冲液的 Bausch + Lomb 溶液使用 CV 测定泰诺（产品标签浓度：661 mmol/L）中的对乙酰氨基酚时，DS 110 显示出更好的灵敏度，但内部 SPCE 是稳定的并且更精确。虽然 DS 110 显示更高的电流，因此更灵敏，但内部 SPCE 电流稳定，因此更精确。从氧化和还原峰获得的浓度对于 DS 110 分别为 (775 ± 80) mmol/L 和 (686 ± 322) mmol/L，对于 in -house SPCE，分别。而且，DS 110 表现出两个大的未知峰，因此在泰诺酚中对乙酰氨基酚 CV 测试中的可靠性较低。实际泰诺样品中对乙酰氨基酚的测定有助于作为 SPCE 制造中的额外质量控制。