Background Mesenchymal Stem Cells can be activated and respond to different bacterial toxins. Lipopolysaccharides (LPS) and Shiga Toxin (Stx) are the two main bacterial toxins present in Hemolytic Uremic Syndrome (HUS) that cause endothelial damage. In this work we aimed to study the response of iPSC-MSC to LPS and/or Stx and its effect on the restoration of injured endothelial cells.

中文翻译：

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细菌脂多糖和志贺毒素对诱导多能干细胞来源间充质干细胞的影响

背景间充质干细胞可以被激活并对不同的细菌毒素作出反应。脂多糖 (LPS) 和志贺毒素 (Stx) 是溶血性尿毒症综合征 (HUS) 中存在的两种主要细菌毒素，可导致内皮损伤。在这项工作中，我们旨在研究 iPSC-MSC 对 LPS 和/或 Stx 的反应及其对受损内皮细胞恢复的影响。