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Xanthohumol Requires the Intestinal Microbiota to Improve Glucose Metabolism in Diet-Induced Obese Mice
Molecular Nutrition & Food Research ( IF 4.5 ) Pub Date : 2021-09-08 , DOI: 10.1002/mnfr.202100389
Isabelle E Logan 1 , Natalia Shulzhenko 2 , Thomas J Sharpton 3, 4 , Gerd Bobe 5 , Kitty Liu 6 , Stephanie Nuss 2 , Megan L Jones 6 , Cristobal L Miranda 7 , Stephany Vasquez-Perez 2 , Jamie M Pennington 8 , Scott W Leonard 8 , Jaewoo Choi 8 , Wenbin Wu 8 , Manoj Gurung 2 , Joyce P Kim 6 , Malcolm B Lowry 9 , Andrey Morgun 10 , Claudia S Maier 11 , Jan F Stevens 7 , Adrian F Gombart 1
Affiliation  

The polyphenol xanthohumol (XN) improves dysfunctional glucose and lipid metabolism in diet-induced obesity animal models. Because XN changes intestinal microbiota composition, the study hypothesizes that XN requires the microbiota to mediate its benefits.

中文翻译:


黄腐酚需要肠道微生物群来改善饮食诱导的肥胖小鼠的葡萄糖代谢



多酚黄腐酚 (XN) 可改善饮食诱导的肥胖动物模型中功能失调的葡萄糖和脂质代谢。由于 XN 会改变肠道微生物群的组成,因此该研究假设 XN 需要微生物群来调节其益处。
更新日期:2021-11-04
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