Background

Despite research linking dissociation, alexithymia, and anger with childhood trauma and ADs, the investigation addressing the relationships between the potential mediators has not yet been established within the literature.

Objective

The present study examined the relationship between childhood trauma and autoimmune disorders, using a multiple mediation model that included dissociation, alexithymia, and anger as hypothesized mediators.

Participants and setting

306 autoimmune patients and 292 self-declared healthy controls were included in the study. They completed self-report questionnaires regarding childhood abuse, alexithymia, dissociation, and anger.

Methods

Multiple mediation analysis was conducted to investigate the study's proposed model.

Results

The results of the Structural Equation Model (SEM) suggest an indirect relationship between childhood trauma and autoimmune disorders, mediated by dissociation [z = 4.57, p < .01, β = 0.19, 90% CI (0.08–0.10)], alexithymia [z = 10.74, p < .01, β = 0.43, 90% CI (0.08–0.10)], but not by anger [z = 1.58, p = .11, 90% CI (0.08–0.10)].

Conclusions

These findings are in line with previous studies that show associations between childhood trauma, dissociation, alexithymia, and ADs. They indicate that mental health professionals and medical doctors should assess childhood trauma in autoimmune patients.

They also should consider the possible maintaining role of dissociation and alexithymia in the treatment of autoimmune diseases.

中文翻译：

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自身免疫性疾病患者的童年创伤、解离、述情障碍和愤怒：一种中介模型

背景

尽管研究将解离、述情障碍和愤怒与童年创伤和 AD 联系起来，但针对潜在中介之间关系的调查尚未在文献中确立。

客观的

本研究使用包括解离、述情障碍和愤怒作为假设中介的多重中介模型，检验了儿童创伤与自身免疫性疾病之间的关系。

参与者和设置

该研究包括 306 名自身免疫患者和 292 名自称健康的对照者。他们完成了关于童年虐待、述情障碍、分离和愤怒的自我报告问卷。

方法

进行了多重中介分析以研究该研究提出的模型。

结果

结构方程模型 (SEM) 的结果表明儿童创伤和自身免疫性疾病之间存在间接关系，由解离介导 [ z  = 4.57, p  < .01, β  = 0.19, 90% CI (0.08–0.10)] z  = 10.74, p  < .01, β  = 0.43, 90% CI (0.08–0.10)]，但不是愤怒 [ z  = 1.58, p  = .11, 90% CI (0.08–0.10)]。

结论

这些发现与之前的研究一致，这些研究表明童年创伤、分离、述情障碍和 AD 之间存在关联。他们表明，心理健康专业人员和医生应该评估自身免疫患者的童年创伤。

他们还应该考虑解离和述情障碍在自身免疫性疾病治疗中的可能维持作用。