In this study, micro- and nanosurface structures were fabricated by sandblasting (S), acid-etching (E), anodic oxidation (A), sandblasting/acid-etching (SE), sandblasting/anodization (SA) and sandblasting/acid-etching/anodization (SEA) processes on Ti6Al4V alloy in order to investigate apatite formation ability. The phase, morphology, topography, roughness and wettability properties of surfaces were characterized by x-ray diffraction (XRD), scanning electron microscopy (SEM), atomic force microscopy (AFM), surface profilometer and contact angle techniques. In vitro tests were performed in simulated body fluid (SBF) for 21 days. The results showed that the surface topography, roughness and wettability changed the Ca and P ion ratio. The SEA sample had high surface topography and the lowest contact angle value. The value of Ca/P ratio was 1.81 for SEA sample. The SEA sample showed the highest Ca/P ratio value which was close to theoretical value. Ca and P ion ratio value because of bioactive phases on the surfaces, high surface roughness and lower contact angle values as compared to other samples. The proposed methodology improves the apatite formation ability of Ti6Al4V alloys. Sandblasted/acid-etched/anodized surfaces can be an alternative to conventional sandblasted/acid-etched implant surfaces.

在这项研究中，微米和纳米表面结构是通过喷砂 (S)、酸蚀刻 (E)、阳极氧化 (A)、喷砂/酸蚀刻 (SE)、喷砂/阳极氧化 (SA) 和喷砂/酸- Ti6Al4V 合金的蚀刻/阳极氧化 (SEA) 工艺，以研究磷灰石的形成能力。通过X射线衍射（XRD）、扫描电子显微镜（SEM）、原子力显微镜（AFM）、表面轮廓仪和接触角技术对表面的相、形貌、形貌、粗糙度和润湿性进行表征。在模拟体液 (SBF) 中进行了 21 天的体外测试。结果表明，表面形貌、粗糙度和润湿性改变了钙磷离子比。SEA 样品具有较高的表面形貌和最低的接触角值。Ca/P 比值为 1。81 为 SEA 样本。SEA 样品显示出最高的 Ca/P 比值，接近理论值。与其他样品相比，由于表面上的生物活性相、高表面粗糙度和较低的接触角值，Ca 和 P 离子比率值。所提出的方法提高了 Ti6Al4V 合金的磷灰石形成能力。喷砂/酸蚀刻/阳极氧化表面可以替代传统的喷砂/酸蚀刻植入物表面。