Object: To evaluate the effects of ultrasound-guided fine-needle aspiration with or without negative pressure (FNA+P or FNA-P) on diagnosis of thyroid nodules.
Methods: A prospective randomized study was performed. Patients (n=1374, female=1094, 79.6%, male=280, 20.4%, age=48.7± 12.5 yr) with thyroid nodules were randomly divided into FNA-P (n=774, 56.3%) and FNA+P (600, 43.7%) groups. Thyroid nodules were diagnosed by FNA-P or FNA+P, in the left (n=640, 46.6%) and right (n=734, 53.4%).
Results: The thyroid nodules were diagnosed as microcalcification (n=751, 54.7%), coarse calcification (n=404, 29.4%), peripheral calcification (n=101, 7.4%) and mixed micro + coarse calcification (n=118, 8.6%). Based on Bethesda classification criteria, the thyroid nodules were cataloged as type I (n=217,15.8%), II (n=467, 34.0%), III (n=151, 11.0%), V (n=333, 24.2%), and VI (n=206, 15.0%). There were no significant differences between experimental groups diagnosed by FNA-P or FNA+P.
Conclusion: The results suggest that fine-needle aspiration with or without negative pressure does not significantly affect the sensitivity of thyroid nodule diagnosis.

Keywords: thyroid nodules, ultrasound-guided fine-needle aspiration, negative pressure, diagnosis


中文翻译：

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不同类型甲状腺结节的超声引导下负压或不负压细针抽吸

目的：评价超声引导下有无负压细针穿刺（FNA+P或FNA-P）对甲状腺结节诊断的影响。
方法：进行了一项前瞻性随机研究。甲状腺结节患者（n=1374，女性=1094, 79.6%，男性=280, 20.4%，年龄=48.7±12.5 岁）随机分为FNA-P（n=774, 56.3%）和FNA+P（ 600, 43.7%) 组。左侧（n=640, 46.6%）和右侧（n=734, 53.4%）通过 FNA-P 或 FNA+P 诊断甲状腺结节。
结果：甲状腺结节诊断为微钙化（n=751, 54.7%）、粗钙化（n=404, 29.4%）、外周钙化（n=101, 7.4%）和混合微+粗钙化（n=118, 8.6%） ）。根据Bethesda分类标准，甲状腺结节分为I型（n=217,15.8%）、II型（n=467, 34.0%）、III型（n=151, 11.0%）、V型（n=333, 24.2） %) 和 VI (n=206, 15.0%)。通过 FNA-P 或 FNA+P 诊断的实验组之间没有显着差异。
结论：结果表明，有或没有负压的细针抽吸对甲状腺结节诊断的敏感性没有显着影响。

【关键词】：甲状腺结节 超声引导下细针穿刺 负压 诊断