Orientational screening is a recently proposed strategy for the selection of DNA templates for silver nanoclusters (AgNCs). The feasibility of this strategy is facilitated by the accumulated experience of synthesizing DNA-templated AgNCs. Herein, a single-stranded DNA template of endowing AgNCs with high brightness (QY = 27.99%) was obtained through an orientational screening process. It was also found that double-stranded DNA rich in GC base pairs could also serve as synthesizing template for AgNCs. A facile method was then developed for the facile assay of bleomycin that might be added in illegally pronouncing products due to its low price and easy accessibility. The detection limit of this method was as low as 4.27 nM, with high sensitivity and good selectivity.

定向筛选是最近提出的用于选择银纳米簇 (AgNC) 的 DNA 模板的策略。这种策略的可行性得益于合成 DNA 模板化 AgNCs 的经验积累。在此， 通过定向筛选过程获得了赋予 AgNCs 高亮度 ( QY = 27.99%)的单链 DNA 模板。还发现富含 GC 碱基对的双链 DNA 也可以作为 AgNCs 的合成模板。然后开发了一种简便的方法来对博来霉素进行简便的检测，由于博来霉素价格低廉且易于获取，因此可能会添加到非法发音的产品中。该方法检测限低至4.27 nM，灵敏度高，选择性好。