Background/Aim: Use of nanomaterials in healthcare applications increases in parallel to technological developments. It is frequently utilized in diagnostic procedures, medications and therapeutic implementations. Nanomaterials take place among key components of medical implants, which might be responsible for certain toxic effects on human health at nano-level. In this review, nanotoxicological effects, toxicity determination of nanobiomaterials used in human body and their effects on human health are discussed.

Materials and Methods: A detailed review of related literature was performed and evaluated as per nanomaterials and medical implants.

Results: The nanotoxic effects of the materials applied to human body and the determination of its toxicity are important. Determination of toxicity for each nanomaterial requires a detailed and multifactorial assessment considering the properties of these materials.

Conclusion: There are limited studies in the literature regarding the toxic effects of nanomaterials used in medical implants. Although these implants are potentially biocompatible and biodegradable, it is highly important to discuss nanotoxicological characteristics of medical implants.

背景/目的：纳米材料在医疗保健应用中的使用随着技术的发展而增加。它经常用于诊断程序、药物和治疗实施。纳米材料发生在医疗植入物的关键部件中，这可能是纳米级对人体健康的某些毒性影响的原因。在这篇综述中，讨论了纳米毒理学效应、用于人体的纳米生物材料的毒性测定及其对人类健康的影响。

材料和方法：根据纳米材料和医疗植入物对相关文献进行了详细审查和评估。

结果：该材料对人体的纳米毒性作用及其毒性测定具有重要意义。考虑到这些材料的特性，确定每种纳米材料的毒性需要进行详细的多因素评估。

结论：关于用于医疗植入物的纳米材料的毒性作用的文献研究有限。尽管这些植入物具有潜在的生物相容性和可生物降解性，但讨论医用植入物的纳米毒理学特性非常重要。