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Resilience to social stress: is it in the blood?
FEBS Open Bio ( IF 2.8 ) Pub Date : 2021-09-08 , DOI: 10.1002/2211-5463.13291
Ruzhica Bogeska 1
Affiliation  

In social mammalian species, social stress can arise from different social interactions. Repeated exposure to social stressors can lead to neuropathology and psychiatric disorders. In this issue, Sakamoto et al. report on alterations in extracellular vesicles (EVs) in a mouse model of chronic social defeat stress (CSDS). The data suggest that mice susceptible to CSDS have alterations in the miRNA content of circulating EVs, which influences the expression of pro-inflammatory cytokines in microglia cells.
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中文翻译:

对社会压力的适应力:它在血液中吗?

在社会哺乳动物物种中,社会压力可能来自不同的社会互动。反复暴露于社会压力源会导致神经病理学和精神疾病。在这个问题上,坂本等人。报告慢性社交失败压力 (CSDS) 小鼠模型中细胞外囊泡 (EV) 的变化。数据表明,易受 CSDS 影响的小鼠循环 EV 的 miRNA 含量发生变化,这会影响小胶质细胞中促炎细胞因子的表达。
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更新日期:2021-10-02
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