Synthesis of 3(5)-aryl-5(3)-pyrazolyl-1,2,4-oxadiazole nitro derivatives,Chemistry of Heterocyclic Compounds

当前位置： X-MOL 学术 › Chem. Heterocycl. Comp. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Synthesis of 3(5)-aryl-5(3)-pyrazolyl-1,2,4-oxadiazole nitro derivatives
Chemistry of Heterocyclic Compounds ( IF 1.4 ) Pub Date : 2021-09-08 , DOI: 10.1007/s10593-021-02987-3
Tatyana K. Shkineva ₁ , Irina A. Vatsadze ₁ , Tigran E. Khoranyan ₁ , Dmitry L. Lipilin ₁ , Igor L. Dalinger ₁ , Alla N. Pivkina ₂

Affiliation

A method was developed for the synthesis of 3(5)-aryl-5(3)-pyrazolyl-1,2,4-oxadiazoles by acylation of amidoximes with acyl chlorides, followed by cyclization of pyrazolyl-O-acylamidoximes into the respective oxadiazoles. Nitration of these products was studied, in combination with nucleophilic substitution reactions in the obtained nitro derivatives.

中文翻译：