Adjunctive rifampicin increases antibiotic efficacy in group A streptococcal tissue infection models,Antimicrobial Agents and Chemotherapy

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Adjunctive rifampicin increases antibiotic efficacy in group A streptococcal tissue infection models
Antimicrobial Agents and Chemotherapy ( IF 4.1 ) Pub Date : 2021-09-07 , DOI: 10.1128/aac.00658-21
H Bergsten ₁ , L M Palma Medina ₁ , M Morgan ₂ , K Moll ₁ , D H Skutlaberg _{3,

4} , S Skrede _{4,

5} , T Wajima ₆ , M Svensson ₁ , A Norrby-Teglund ₁

Affiliation

Objectives: Biofilm has recently been highlighted as a complicating feature of necrotizing soft tissue infections (NSTI) caused by Streptococcus pyogenes (i.e. group A streptococcus; GAS) contributing to a persistence of bacteria in tissue despite ...

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