RNAi is a major plant antiviral strategy. However, the mechanisms triggering RNAi are unknown. In this issue of Cell Host & Microbe, Wang et al. (2021) demonstrate that wound-induced calcium signaling induces RNAi activation. As a counter-defense, a viral suppressor of RNAi (VSR) interferes with players in calcium signaling.

中文翻译：

---

Ca2+ 启动抗病毒 RNAi

RNAi 是一种主要的植物抗病毒策略。然而，触发 RNAi 的机制尚不清楚。在本期Cell Host & Microbe中，Wang 等人。(2021) 证明伤口诱导的钙信号可诱导 RNAi 激活。作为一种反防御，RNAi (VSR) 的病毒抑制因子会干扰钙信号传导的参与者。