Purpose of Review

The burden of cardiometabolic diseases such as cardiovascular disease (CVD) and type 2 diabetes (T2D) is pronounced among African Americans. Research has shown that behavioral, social, metabolic, psychosocial, and genetic risk factors of CVD and T2D are closely interwoven. Approximately 20 years ago, the Jackson Heart Study (JHS) was established to investigate this constellation of risk factors.

Recent Findings

Findings from neighborhood studies emphasize the importance of social cohesion and physical environment in the context CVD and T2D risk. Socioeconomic status factors such as income and education were significant predictors for CVD and T2D. Behavioral studies indicate that modifiable risk factors such as smoking, physical inactivity, lack of sleep, and poor nutrition are associated with CVD risk and all-cause mortality. Mental health also was found to be associated with CVD and T2D. Genetic influences are associated with disease etiology.

Summary

This review summarizes the joint contributions of CVD and cardiometabolic risk factors in an African American population.

中文翻译：

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杰克逊心脏研究教会了我们关于非裔美国人社区糖尿病和心血管疾病的知识：20 年的赞赏

审查目的

在非裔美国人中，心血管疾病 (CVD) 和 2 型糖尿病 (T2D) 等心脏代谢疾病的负担很明显。研究表明，CVD 和 T2D 的行为、社会、代谢、社会心理和遗传风险因素密切相关。大约 20 年前，杰克逊心脏研究 (JHS) 成立以调查这一系列风险因素。

最近的发现

邻里研究的结果强调了社会凝聚力和物理环境在 CVD 和 T2D 风险中的重要性。收入和教育等社会经济地位因素是 CVD 和 T2D 的重要预测因素。行为研究表明，吸烟、缺乏身体活动、睡眠不足和营养不良等可改变的风险因素与 CVD 风险和全因死亡率相关。还发现心理健康与 CVD 和 T2D 相关。遗传影响与疾病病因有关。

概括

本综述总结了非裔美国人人群中 CVD 和心脏代谢危险因素的共同作用。