Abstract

The use of modifiers in the electrophoretic separation of multicomponent mixtures makes it possible to significantly expand the analytical capabilities of capillary electrophoresis. Modifiers of electrophoretic systems, different in nature and properties, can perform different functions: form stationary and pseudo-stationary phases, prevent the adsorption of analytes on the walls of a quartz capillary, help to reduce the limits of detection for analytes during preconcentration, etc. In this review, various versions of the application of modifiers to the electrophoretic separation and preconcentration of analytes of different nature are considered on an example of imidazolium ionic liquids, which can act as stationary and pseudo-stationary phases, and also directly participate in the online preconcentration of analytes of hydrophilic and hydrophobic nature.

中文翻译：

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改性剂对生物活性化合物电泳分离和毛细管间预浓缩的影响

摘要

在多组分混合物的电泳分离中使用改性剂可以显着扩展毛细管电泳的分析能力。不同性质和性质的电泳系统改性剂可以执行不同的功能：形成固定相和假固定相，防止分析物吸附在石英毛细管壁上，有助于降低预浓缩过程中分析物的检测限等. 在这篇综述中，以咪唑鎓离子液体为例，考虑了将改性剂应用于不同性质的分析物的电泳分离和预浓缩的各种版本，它可以作为固定相和假固定相，