Nanocarriers-based immobilization strategies are a novel concept in the enhancement of enzyme stability, shelf life and efficiency. A wide range of natural and artificial supports have been assessed for their efficacy in enzyme immobilization. Nanomaterials epitomize unique and fascinating matrices for enzyme immobilization. These structures include carbon nanotubes, superparamagnetic nanoparticles and nanofibers. These nano-based supports offer stable attachment of enzymes, thus ensuring their reusability in diverse industrial applications. This review attempts to encompass recent developments in the critical role played by nanotechnology towards the improvement of the practical applicability of microbial enzymes. Nanoparticles are increasingly being used in combination with various polymers to facilitate enzyme immobilization. These endeavors are proving to be conducive for enzyme-catalyzed industrial operations. In recent years the diversity of nanomaterials has grown tremendously, thus offering endless opportunities in the form of novel combinations for various biotransformation experimentations. These nanocarriers are advantageous for both free enzymes and whole-cell immobilization, thus demonstrating to be relatively effective in several fermentation procedures.

基于纳米载体的固定化策略是提高酶稳定性、保质期和效率的一个新概念。已经评估了广泛的天然和人工支持物在酶固定中的功效。纳米材料是酶固定化独特而迷人的基质的缩影。这些结构包括碳纳米管、超顺磁性纳米颗粒和纳米纤维。这些基于纳米的支持物提供酶的稳定附着，从而确保它们在各种工业应用中的可重复使用性。本综述试图涵盖纳米技术在提高微生物酶的实际适用性方面发挥的关键作用的最新进展。纳米颗粒越来越多地与各种聚合物结合使用，以促进酶的固定化。这些努力被证明有利于酶催化的工业操作。近年来，纳米材料的多样性急剧增加，从而为各种生物转化实验提供了无限的机会。这些纳米载体对于游离酶和全细胞固定都是有利的，因此证明在几种发酵过程中相对有效。