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A randomized controlled trial of antibody response to 2019-20 cell-based inactivated and egg-based live attenuated influenza vaccines in children and young adults
medRxiv - Infectious Diseases Pub Date : 2021-09-06 , DOI: 10.1101/2021.09.02.21263043 Katherine V Williams , Bo Zhai , John F Alcorn , Mary Patricia Nowalk , Min Z Levine , Sara Kim , Brendan Flannery , Krissy Moehling Geffel , Amanda Jaber Merranko , Jennifer P Nagg , Mark Collins , Michael Susick , Karen S Clarke , Richard K Zimmerman , Judith M Martin
medRxiv - Infectious Diseases Pub Date : 2021-09-06 , DOI: 10.1101/2021.09.02.21263043 Katherine V Williams , Bo Zhai , John F Alcorn , Mary Patricia Nowalk , Min Z Levine , Sara Kim , Brendan Flannery , Krissy Moehling Geffel , Amanda Jaber Merranko , Jennifer P Nagg , Mark Collins , Michael Susick , Karen S Clarke , Richard K Zimmerman , Judith M Martin
Background Hemagglutination inhibition (HAI) titers to the live-attenuated influenza vaccine (LAIV4) are typically lower than its counterpart egg-based inactivated influenza vaccines (IIV). Similar comparisons have not been made between LAIV4 and the 4-strain, cell-culture inactivated influenza vaccine (ccIIV4). We compared healthy children and young adult HAI titers against the 2019-2020 LAIV4 and ccIIV4.
中文翻译：
儿童和青年对 2019-20 年基于细胞的灭活和基于鸡蛋的减毒活流感疫苗的抗体反应的随机对照试验
背景减毒活流感疫苗 (LAIV4) 的血凝抑制 (HAI) 滴度通常低于其对应的基于鸡蛋的灭活流感疫苗 (IIV)。在 LAIV4 和 4 株细胞培养灭活流感疫苗 (ccIIV4) 之间尚未进行类似的比较。我们将健康儿童和年轻成人的 HAI 滴度与 2019-2020 LAIV4 和 ccIIV4 进行了比较。
更新日期：2021-09-08
中文翻译：
儿童和青年对 2019-20 年基于细胞的灭活和基于鸡蛋的减毒活流感疫苗的抗体反应的随机对照试验
背景减毒活流感疫苗 (LAIV4) 的血凝抑制 (HAI) 滴度通常低于其对应的基于鸡蛋的灭活流感疫苗 (IIV)。在 LAIV4 和 4 株细胞培养灭活流感疫苗 (ccIIV4) 之间尚未进行类似的比较。我们将健康儿童和年轻成人的 HAI 滴度与 2019-2020 LAIV4 和 ccIIV4 进行了比较。
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