Organocatalytic Enantioselective Michael-Aldol[3+2] Annulation for the Synthesis of Nitro-Methanobenzo[7] annulenes,European Journal of Organic Chemistry

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Organocatalytic Enantioselective Michael-Aldol[3+2] Annulation for the Synthesis of Nitro-Methanobenzo[7] annulenes
European Journal of Organic Chemistry ( IF 2.5 ) Pub Date : 2021-09-08 , DOI: 10.1002/ejoc.202100974
Yang Zhang ₁ , Jin-Yu Liu ₂ , Xiao-Hai Zhang ₃

Affiliation

An enantioselective Michael-Aldol[3+2] annulation via bifunctional thiourea catalysis has been reported, and a series of nitro-methanobenzo[7]annulenes with potential biological activities were synthesized in good yields with excellent enantio- and diastereoselectivities.