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Differential Effects of Prostaglandin D2 Signaling on Macrophages and Microglia in Murine Coronavirus Encephalomyelitis
mBio ( IF 5.1 ) Pub Date : 2021-09-07 , DOI: 10.1128/mbio.01969-21
Abhishek Kumar Verma 1 , Jian Zheng 1 , Matthias Mack 2 , Florent Ginhoux 3, 4, 5 , Stanley Perlman 1
Affiliation  

Current understanding about the roles of microglia versus macrophages in viral encephalitis is limited. We previously showed that the signaling of a single prostaglandin, PGD2, through its DP1 receptor on myeloid cells is critical for optimal immune ...

中文翻译:

前列腺素 D2 信号转导对小鼠冠状病毒脑脊髓炎巨噬细胞和小胶质细胞的差异影响

目前对小胶质细胞与巨噬细胞在病毒性脑炎中的作用的了解有限。我们之前表明,单个前列腺素 PGD2 通过其骨髓细胞上的 DP1 受体的信号传导对于最佳免疫...
更新日期:2021-09-12
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