A growing number of publications are identified toward the use of black cumin seeds (Nigella sativa L) on small ruminant animals since many beneficial evidences have been reported in humans and animals. This study used a meta-analysis approach to quantify the effect of black cumin seeds (BCS) supplementation on the productive performance, nutrients utilization, and blood metabolites profile of small ruminant animals. Following the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) protocols, a total of 23 studies were aggregated in a database and were analyzed using mixed model methodology classifying the studies as random effects and levels of BCS as fixed effects in the models. Results found that interaction between BCS levels and animal species tended to be significant whereas increasing dietary BCS levels linearly increased average daily gain (ADG) (p < 0.01, R² = 0.538) and dry matter intake in lambs (p < 0.01, R² = 0.958) but had no effect on sheep. Nitrogen (N) intake, and N digested were found to be significantly increased (p < 0.01) as inclusion rates of BCS increased while organic matter (OM), crude protein (CP), and ether extract (EE) intakes tended to increased (p < 0.10). In addition to other immune responses, strong positive relationships were found on the increase of concentration of IgA (R² = 0.922) and IgG (R² = 0.939) (p < 0.05) in response to increasing BCS supplementation. To conclude, black cumin seeds can be used as a safe and beneficial feed supplement to promote the growth of small ruminant animals such as lambs, sheep, and goats.

越来越多的出版物被确定为使用黑孜然种子（Nigella sativaL) 在小型反刍动物身上，因为在人类和动物身上已经报道了许多有益的证据。本研究使用荟萃分析方法来量化补充黑孜然种子 (BCS) 对小型反刍动物的生产性能、营养利用和血液代谢物谱的影响。遵循系统评价和元分析的首选报告项目 (PRISMA) 协议，总共 23 项研究汇总在一个数据库中，并使用混合模型方法进行分析，将研究分类为随机效应，将 BCS 水平分类为模型中的固定效应. 结果发现 BCS 水平与动物物种之间的相互作用往往是显着的，而增加膳食 BCS 水平线性增加平均日增重 (ADG) (p < 0.01, R ² = 0.538）和羔羊的干物质摄入量（p < 0.01，R ²  = 0.958），但对绵羊没有影响。发现氮 (N) 摄入量和消化的 N 显着增加 (p < 0.01)，因为 BCS 的加入率增加，而有机物 (OM)、粗蛋白 (CP) 和醚提取物 (EE) 的摄入量趋于增加（ p < 0.10)。除了其他免疫反应外，还发现 IgA (R ²  = 0.922) 和 IgG (R ²  = 0.939) (p < 0.05)的浓度随着 BCS 补充剂的增加而增加。总而言之，黑孜然种子可以作为一种安全有益的饲料补充剂，促进小反刍动物如羔羊、绵羊和山羊的生长。