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Is SARS-CoV-2 infection an emerging risk factor for splanchnic venous thrombosis?
Clinical Hemorheology and Microcirculation ( IF 2.1 ) Pub Date : 2021-09-05 , DOI: 10.3233/ch-211256
Cesare Tripolino 1 , Attilia Maria Pizzini 1 , Stefania Zaccaroni 1 , Camilla Cicognani 1 , Susanna Dapporto 1 , Maria Luigia Cipollini 1 , Claudia Giannone 1 , Carlotta Cavoli 1 , Mauro Silingardi 1
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OBJECTIVE:Thrombosis represents one of the most feared complications of the COronaVIrus Disease-2019 (COVID-19). Although pulmonary embolism and deep venous thrombosis are the most described complications, some investigations reported thrombotic localization also in the splanchnic venous district.METHODS:We describe the case of a patient with SARS-CoV-2 infection presenting with abdominal pain and diagnosed with portal vein thrombosis. In addition, we shortly review available literature supporting the possible role of COVID-19 as leading cause of splanchnic venous thrombosis. RESULTS:After in-depth diagnostic workup, we excluded the commonest causes of portal thrombosis and concluded that SARS-CoV-2 infection represented the main explanation of this finding. CONCLUSIONS:Our study warns the clinicians to maintain a high index of suspicion for thrombosis in patients diagnosed with SARS-CoV-2 infection manifesting gastrointestinal symptoms. An appropriate diagnostic work-up could allow to obtain an early diagnosis and consequently improve the clinical outcome of patients.

中文翻译:

SARS-CoV-2 感染是内脏静脉血栓形成的新兴危险因素吗?

目标:血栓形成是 2019 年冠状病毒病 (COVID-19) 最令人恐惧的并发症之一。虽然肺栓塞和深静脉血栓形成是最常描述的并发症,但一些研究报告内脏静脉区也有血栓形成。血栓形成。此外,我们很快回顾了现有文献,这些文献支持 COVID-19 可能是内脏静脉血栓形成的主要原因。结果:经过深入的诊断检查,我们排除了门静脉血栓形成的最常见原因,并得出结论认为 SARS-CoV-2 感染是这一发现的主要解释。结论:我们的研究警告临床医生对诊断为 SARS-CoV-2 感染并表现出胃肠道症状的患者保持高度怀疑血栓形成。适当的诊断检查可以允许获得早期诊断并因此改善患者的临床结果。
更新日期:2021-09-07
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