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Chelation-Tamoxifen Conjugates for Imaging of Estrogen Receptors
Cancer Biotherapy and Radiopharmaceuticals ( IF 2.4 ) Pub Date : 2022-02-08 , DOI: 10.1089/cbr.2021.0169
Skye Hsin-Hsien Yeh, Wei-Chung Chang, Shu-Meng Hsu, Ming Hsien Lin, Min-Ching Chung, Chi-Shiang Ke, Yen-Chun Lee, Chorng-Jer Hwang, David J. Yang

Background: The differential diagnosis of estrogen receptor-positive (ER+) pathway-activated systems by using a labeled antiestrogen helps to select the patients for optimal response to endocrine therapy and to discontinue the treatment when resistance occurs. The authors' purpose was to synthesize chelator-tamoxifen conjugates for imaging ER (+) diseases.

中文翻译:

用于雌激素受体成像的螯合-他莫昔芬偶联物

背景:使用标记的抗雌激素对雌激素受体阳性 (ER+) 通路激活系统进行鉴别诊断有助于选择对内分泌治疗产生最佳反应的患者,并在发生耐药时停止治疗。作者的目的是合成用于成像 ER (+) 疾病的螯合剂-他莫昔芬偶联物。
更新日期:2022-02-09
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