Plasma catecholamine levels in the acute and subacute stages of takotsubo syndrome: Results from the Stockholm myocardial infarction with normal coronaries 2 study,Clinical Cardiology

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Plasma catecholamine levels in the acute and subacute stages of takotsubo syndrome: Results from the Stockholm myocardial infarction with normal coronaries 2 study
Clinical Cardiology ( IF 2.4 ) Pub Date : 2021-09-07 , DOI: 10.1002/clc.23723
Shams Y-Hassan ₁ , Peder Sörensson ₂ , Christina Ekenbäck ₃ , Magnus Lundin ₄ , Stefan Agewall ₅ , Elin Bacsovics Brolin _{6,

7} , Kenneth Caidahl ₄ , Kerstin Cederlund _{6,

8} , Olov Collste ₉ , Maria Daniel ₉ , Jens Jensen ₁₀ , Claes Hofman-Bang ₃ , Patrik Lyngå ₉ , Eva Maret ₄ , Nondita Sarkar ₁₁ , Jonas Spaak ₃ , Oscar Winnberg ₁₀ , Martin Ugander _{4,

12} , Per Tornvall ₉ , Loghman Henareh ₁

Affiliation

Coronary Artery Disease Area, Heart and Vascular Theme, Karolinska Institute and Karolinska University Hospital, Stockholm, Sweden.
Department of Medicine Solna, Karolinska Institutet, and Department of Cardiology, Karolinska University Hospital, Stockholm, Sweden.
Division of Cardiovascular Medicine, Karolinska Institutet, Department of Clinical Sciences, Danderyd Hospital, Stockholm, Sweden.
Department of Clinical Physiology, Karolinska University Hospital, and Karolinska Institutet, Stockholm, Sweden.
Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
Department of Clinical Science, Division of Medical Imaging and Technology, Intervention and Technology at Karolinska Institutet, Stockholm, Sweden.
Department of Radiology, Capio S:t Görans Hospital, Stockholm, Sweden.
Department of Radiology, Södertälje Hospital, Södertälje, Sweden.
Department of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, and Cardiology Unit, Södersjukhuset, Stockholm, Sweden.
Department of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, and Department of Cardiology, Capio St: Görans Hospital, Stockholm, Sweden.
Department of Cardiology, Karolinska University Hospital, Stockholm, Sweden.
Kolling Institute, Royal North Shore Hospital, and Charles Perkins Centre, Faculty of Medicine and Health, University of Sydney, Sydney, Australia.

It is well-accepted that takotsubo syndrome (TS) is characterized by a massive surge of plasma catecholamines despite lack of solid evidence. The objective of this study was to examine the hypothesis of a massive catecholamine elevation in TS by studying plasma-free catecholamine metabolites in patients participating in the Stockholm myocardial infarction (MI) with normal coronaries 2 (SMINC-2) study where TS constituted more than one third of the patients.

中文翻译：

takotsubo 综合征急性和亚急性阶段的血浆儿茶酚胺水平：斯德哥尔摩心肌梗塞冠状动脉正常的结果 2 研究

尽管缺乏确凿的证据，人们普遍认为 takotsubo 综合征 (TS) 的特点是血浆儿茶酚胺大量激增。本研究的目的是通过研究参加斯德哥尔摩心肌梗死 (MI) 冠状动脉正常 2 (SMINC-2) 研究的患者的血浆游离儿茶酚胺代谢物，来检验 TS 中儿茶酚胺大量升高的假设，其中 TS 构成超过三分之一的患者。

更新日期：2021-11-07

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