Prompt recognition and treatment of presumed bacterial infection in febrile children with sickle cell disease is necessary due to splenic dysfunction and impaired immune response. However, fever may be a manifestation of a noninfectious process, and health care providers must consider alternative sources. We describe 2 cases of children with sickle cell disease and persistent fevers, ultimately diagnosed with Kawasaki disease. These cases provide examples of an acute febrile illness that could lead to serious consequences if differential diagnoses are not considered and treatment is delayed.

中文翻译：

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镰状细胞病患儿川崎病病例系列。

由于脾脏功能障碍和免疫反应受损，有必要及时识别和治疗镰状细胞病发热儿童的疑似细菌感染。然而，发烧可能是非感染过程的表现，医疗保健提供者必须考虑其他来源。我们描述了 2 例患有镰状细胞病和持续发烧的儿童，最终诊断为川崎病。这些病例提供了急性发热性疾病的例子，如果不考虑鉴别诊断并延误治疗，可能会导致严重后果。