Decades of research have informed our understanding of how stress impacts the brain to perturb behavior. However, stress during development has received specific attention as this occurs during a sensitive period for scaffolding lifelong socio-emotional behavior. In this review, we focus the developmental neurobiology of stress-related pathology during infancy and focus on one of the many important variables that can switch outcomes from adaptive to maladaptive outcome: caregiver presence during infants' exposure to chronic stress. While this review relies heavily on rodent neuroscience research, we frequently connect this work with the human behavioral and brain literature to facilitate translation. Bowlby's Attachment Theory is used as a guiding framework in order to understand how early care quality impacts caregiver regulation of the infant to produce lasting outcomes on mental health.

中文翻译：

---

婴儿依恋和压力神经生物学的社会改变。


数十年的研究让我们了解了压力如何影响大脑并扰乱行为。然而，发育过程中的压力受到了特别关注，因为这种压力发生在支撑终生社会情感行为的敏感时期。在这篇综述中，我们重点关注婴儿期压力相关病理学的发育神经生物学，并重点关注可以将结果从适应性结果转变为适应不良结果的许多重要变量之一：婴儿暴露于慢性压力期间照顾者的存在。虽然这篇综述在很大程度上依赖于啮齿动物神经科学研究，但我们经常将这项工作与人类行为和大脑文献联系起来以促进翻译。鲍尔比的依恋理论被用作指导框架，以了解早期护理质量如何影响护理人员对婴儿的调节，从而产生持久的心理健康结果。