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Haematological malignancies in sub-Saharan Africa: east Africa as an example for improving care.
The Lancet Haematology ( IF 15.4 ) Pub Date : 2021-09-02 , DOI: 10.1016/s2352-3026(21)00198-8
Clement D Okello 1 , Nixon Niyonzima 1 , Marta Ferraresso 2 , Sylivestor Kadhumbula 1 , Henry Ddungu 1 , Katherine Tarlock 3 , Joyce Balagadde-Kambugu 1 , Abrahams Omoding 1 , Louis Ngendahayo 4 , Alfred Karagu 5 , Julius Mwaiselage 6 , John M Harlan 7 , Thomas S Uldrick 8 , Suzanne D Turner 2 , Jackson Orem 1
Affiliation  

Haematological malignancies account for almost 10% of all cancers diagnosed in sub-Saharan Africa, although the exact incidences and treatment outcomes are difficult to discern because population-based cancer registries in the region are still underdeveloped. More research on haematological malignancies in sub-Saharan Africa is required to establish whether these cancers have a natural history similar to those diagnosed in high-income countries, about which more is known. Several factors negatively affect the outcome of haematological malignancies in sub-Saharan Africa, showcasing a need for improved understanding of the clinicobiological profile of these cancers to facilitate prevention, early detection, diagnosis, and appropriate treatment through increased capacity building, infrastructure, community awareness, coordinated resource mobilisation, and collaboration across the world. The east African governments have pooled resources for common investments to tackle non-communicable diseases, developing the East Africa's Centres of Excellence for Skills and Tertiary Education project funded by the African Development Bank, an initiative that could be replicated for the care of haematological malignancies in other countries in sub-Saharan Africa. TRANSLATION: For the French translation of the abstract see Supplementary Materials section.

中文翻译:


撒哈拉以南非洲的血液恶性肿瘤:以东非为例改善护理。



在撒哈拉以南非洲地区,血液系统恶性肿瘤几乎占诊断出的所有癌症的 10%,但由于该地区基于人群的癌症登记仍然不发达,因此很难确定确切的发病率和治疗结果。需要对撒哈拉以南非洲地区的血液恶性肿瘤进行更多研究,以确定这些癌症是否具有与高收入国家诊断出的癌症相似的自然病史,而人们对此了解得更多。有几个因素对撒哈拉以南非洲血液恶性肿瘤的结果产生负面影响,表明需要更好地了解这些癌症的临床生物学特征,以通过加强能力建设、基础设施、社区意识、促进预防、早期发现、诊断和适当治疗。协调资源调动和全球合作。东非各国政府汇集了资源进行共同投资,以应对非传染性疾病,开发了由非洲开发银行资助的东非技能和高等教育卓越中心项目,这一举措可以在东非血液系统恶性肿瘤的治疗中推广。撒哈拉以南非洲的其他国家。翻译:有关摘要的法文翻译,请参阅补充材料部分。
更新日期:2021-09-01
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