Environmental issues pertaining to global warming and pollution have become a global concern and solutions are, therefore, being urgently sought with a wide ranging application of suitable entity to minimize the energy consumption while curbing associated economic costs. Prussian blue (PB) (${\text{Fe}}_4^{3+}{\left[\mathrm{F}{\mathrm{e}}^{2+}{\left(\text{CN}\right)}_6\right]}_3$) and its PB analogous (PBA) (${\mathrm{A}}_2\mathrm{T}\left[\mathrm{M}{\left(\text{CN}\right)}_6\right]$, A=Li, K, Na; T=Fe, Co, Ni, Mn, Cu, etc.; M=Fe, Mn, Co, etc.) are metal organic frameworks that have numerous appliances and have garnered major attention in recent years. However, there are only handful of reviews discussing the fundamental catalytic properties of PB-based materials and hence this effort to comprehensively review and systematically discuss the critical role of PB-based materials in broader catalytic context embracing environment and the energy aspects. Initially, the fundamentals and principles of underlying processes are elucidated followed by a detailed discussion on the catalytic performance and applications of PBA-based catalysts in advanced oxidation processes, reduction reactions, water splitting, and miscellaneous applications, among others. This comprehensive overview features details of the broad catalytic activities of PBA-based materials in diverse applications and hopefully would be a reference on PBA-centered catalysts in an array of applications including industrial applications.